Synchronous Antithyroid Drug-Induced Agranulocytosis and Fournier Gangrene
نویسندگان
چکیده
منابع مشابه
Antithyroid drug-induced agranulocytosis.
Antithyroid drugs are widely used to treat hyperthyroidism, especially Graves' disease, but they tend to cause agranulocytosis, which increases the mortality rate. Granulocyte colony-stimulating factor decreases the duration of recovery from agranulocytosis. We retrospectively studied cases of antithyroid drug-induced agranulocytosis over the past 10 years in a northern Taiwan medical center. A...
متن کاملAntithyroid drug-induced agranulocytosis.
Thyrotoxicosis is a common endocrine disorder. Antithyroid drug therapy is the standard treatment for this disease, especially in young women of reproductive age. A serious side effect of antithyroid drug use, however, is agranulocytosis. We report on two patients with antithyroid drug-induced agranulocytosis. Both patients presented with fever and severe neutropenia. The administration of gran...
متن کاملAntithyroid drug-induced agranulocytosis: report of 13 cases.
BACKGROUND Antithyroid drug (ATD)-induced agranulocytosis is rare but may cause fatal complications in patients with thyrotoxicosis during treatment with thionamide-derived drugs. From our previous experience, we note that 2 of 11 such patients died in a 10-year retrospective study. METHODS We reviewed thirteen patients who developed agranulocytosis from 7,466 patients with hyperthyroidism wh...
متن کاملFournier Gangrene
A 51-year-old male with hepatitis C and a history of intravenous (IV) drug use presented to the emergency department, reporting one day of worsening scrotal pain and swelling. He denied diabetes, trauma, or infection with HIV. His genitourinary examination revealed a draining lesion in his left inguinal region with surrounding induration and cellulitis extending onto his perineum. His scrotum w...
متن کاملFournier gangrene
Fournier gangrene is a rapidly progressive necrotizing infection of the perineal and genital fascia, often polymicrobial. Severity is increased in older patients, diabetics and the immunocompromised. As in this case, the disease can have an indolent onset. Early recognition and aggressive treatment is important.
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ژورنال
عنوان ژورنال: AACE Clinical Case Reports
سال: 2018
ISSN: 2376-0605
DOI: 10.4158/ep171801.cr